Journal: Pharmaceutics
Article Title: Composition Dependency of the Flory–Huggins Interaction Parameter in Drug–Polymer Phase Behavior
doi: 10.3390/pharmaceutics15122650
Figure Lengend Snippet: Flory–Huggins interaction parameter depending on the drug volume fraction of solid dispersions containing the drugs acetaminophen ( top ), itraconazole ( middle ), griseofulvine ( bottom ), and the polymers basic butylated methacrylate copolymer ( left ), Soluplus ® ( middle ), and polyvinylpyrrolidone/vinyl acetate copolymer ( right ).
Article Snippet: Furthermore, the polymers basic butylated methacrylate copolymer (bBMA) EUDRAGIT ® E PO (Evonik Industries AG, Darmstadt, Germany), vinylpyrrolidone/vinyl acetate copolymer (PVPVA) Kollidon ® VA64 (BASF SE, Ludwigshafen, Germany), and Soluplus ® (SOL) (BASF SE, Ludwigshafen, Germany), an ethylene glycol/vinylcaprolactam/vinyl acetate copolymer, were selected.
Techniques: